EFFECT OF DIETARY INTERVENTION ON REDUCING LEVEL OF THE HYPERURICEMIA IN EXPERIMENTAL ANIMALS

Document Type : Original Article

Authors

Nut. Biochem. and Metabolism Dept., Nat. Nut. Inst., Egypt

Abstract

This study was carried out to investigate the effect of dietary intervention of different concentrations (5% and 10%) from parsley (seeds and leaves), cherry and tomato on hyperuricemia in rats. This study was carried on 80 male albino rats; Sprague-Dawley strain weighing (130±10 g). The experimental period was 6 weeks. The results showed significant decrease (P<0.05) in serum uric acid and urea nitrogen as compared to positive control (+ve) and also significant decrease (P<0.05) in serum total cholesterol, triglycerides and VLDL-C as compared to control positive group. The best results of histological examination of liver were in rats group treated with 5 and 10% cherry followed by parsley seeds and leaves 10%. While the best histological examinations of kidney were observed in parsley seeds and leaves 10% followed by 5%.  It could be concluded that parsley (leaves and seeds), tomato and cherry reduce serum uric acid and urea nitrogen levels and improve kidney and liver functions.

Keywords

Zagazig Journal of Agricultural Research
Volume 43, Issue 1
January 2016
Pages 195-208

Files

Share

How to cite

Statistics